Topics Molecular Medicine
Molecular Medicine
1. Role of FoxO1 transcription factor in B-cell malignancies
Supervisor: Prof. MUDr. Mgr. Marek Mráz, Ph.D.; Research group: Microenvironment of Immune Cells
Keywords: CLL, FoxO1, targeted therapy, microenvironment, apoptosis
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2. Long non-coding RNAs (IncRNAs) in the pathogenesis of mature B cell malignancies
Supervisor: Prof. MUDr. Mgr. Marek Mráz, Ph.D.; Research group: Microenvironment of Immune Cells
Keywords: Long non-coding RNA, lymphomas, DLBCL, miRNA
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3. Regulation of microenvironmental interactions in chronic lymphocytic leukemia by non-coding RNAs
Supervisor: Mgr. Miroslav Boudný, Ph.D.; Consultant: doc. MUDr. Mgr. Marek Mráz, Ph.D.
Research group: Microenvironment of Immune Cells
Keywords: miRNA, CLL, T cell, microenvironment
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4. Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression and tumorigenesis
Supervisor: Mgr. Dalibor Blažek, Ph.D.; Research group: Inherited Diseases - Transcriptional Regulation
Keywords: CDK11, transcription, mRNA processing, RNA polymerase II, cancer, genomics, proteomics, kinase inhibitors
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Supervisor: Mgr. Dalibor Blažek, Ph.D.; Research group: Inherited Diseases - Transcriptional Regulation
Keywords: CDK12, transcription, mRNA processing, RNA polymerase II, cancer, genomics, proteomics, kinase inhibitors
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6 . Development of bioinformatics methods for radiogenomics approaches in cancer research
Supervisor: Mgr. Vojtěch Bystrý, Ph.D.; Core facility: Bioinformatics Core Facility
Keywords: bioinformatics, radiogenomics, cancer research, genomics, radiomics, spatial transcriptomic
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7. Role of the transcription factors in onset and progression of B-Cell malignancies
Supervisor: RNDr. Josef Večeřa, Ph.D.; Research group: Microenvironment of Immune Cells
Keywords: CLL, transcription factor, epigenetics, microenvironment
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8. FoxO transcription factors in lymphoproliferative diseases
Supervisor: Mgr. Václav Šeda, Ph.D.; Research group: Microenvironment of Immune Cells
Keywords: CLL, B cell malignancies, BCR signalling, FoxO1, targeted therapy
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